Do not use Zyban if:

• you are allergic to any ingredient in Zyban;
• you are taking any other medicine that contains bupropion;
• you have a history of an eating disorder (e.g., anorexia, bulimia) or seizures (e.g., epilepsy);
• you are suddenly stopping the use of alcohol or sedatives (e.g., benzodiazepines) after long-term use;
• Contact your doctor or health care provider right away if any of these apply to you.
  
  Important:
  • Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not take decongestants (e.g., pseudoephedrine), stimulants, or diet pills while you are taking Zyban without first checking with your doctor. They may increase your risk of seizures.
  • If you have trouble sleeping, you may be taking your dose too close to bedtime. Talk with your doctor about changing your dosing schedule.
  • It is important to follow the program that your doctor has prescribed, including behavioral changes, counseling, or support services, in order to stop smoking.
  • Zyban can be used together with the nicotine skin patches only under the supervision of your doctor. Using these medicines together may raise your blood pressure. If you are already using a nicotine skin patch, your blood pressure should be checked regularly.
  • Do not smoke if you are using Zyban along with the nicotine skin patch or any nicotine product.
  • Stopping smoking may change the amount of certain medicines (e.g., theophylline, warfarin) in your blood. Be sure your doctor knows all the medicines that you are taking.
  • Zyban contains the same ingredients as Wellbutrin, an antidepressant. Do not take Zyban if you are also taking Wellbutrin or other brands of bupropion. Discuss any questions or concerns with your doctor.
  • Use Zyban with caution in the elderly; they may be more sensitive to its effects.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zyban while you are pregnant. Zyban is found in breast milk. Do not breast-feed while taking Zyban.

    
    Possible Side Effects
    
    

    Check with your doctor if any of these most common side effects persist or become bothersome:

    • anxiety; constipation; diarrhea; dizziness; drowsiness; dry mouth; loss of appetite; nausea; nervousness; stomach pain; stuffy nose; trouble sleeping.
    Seek medical attention right away if any of these severe side effects occur:
    • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; chest pain; concentration problems, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated sense of well-being, inability to sit still, or other unusual or severe mental or mood changes; confusion; changes in sexual desire or ability; delusions; fainting; fast or irregular heartbeat; fever or chills; hallucinations; hearing problems or ringing in the ears; joint or muscle pain; menstrual changes; red, swollen, blistered, or peeling skin; seizures; severe headache or dizziness; severe or persistent anxiety, agitation, restlessness, or trouble sleeping; shortness of breath; suicidal thoughts or attempts; tremor.
    
    
    More Information
    
    

    Zyban is to be used only by the patient for whom it is prescribed. Do not share it with other people.