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	Ted Kennedy brain tumour malignant glioma, ted kennedy, parietal lobe, glioblastoma, left parietal lobe The Americans were shocked to learn that a malignant brain tumor was the cause of Senator Ted Kennedy 's collapse of a weekend. While his doctors announced courses of treatment of chemotherapy and radiation, the tumor was identified as glioma, an aggressive form of cancer. The U.S. company for neurology said that gliomas are very harmful because they exclude rapidly in the brain. More than half the patients diagnosed with a glioma die within 18 months. The diagnosis dominated news bulletins U.S. overnight and prompted widespread tributes to the "long-serving; Lion of the Senate". President George Bush said he was deeply saddened and that he would request for Senator Kennedy. "Ted Kennedy is a man of enormous courage, strength remarkably and spirit strong. Our thoughts are with Senator Kennedy and his family during this difficult period," Mr. Bush said. One of those who hopes to succeed the president, Barack Obama, said he was shattered by the news. Senator Obama said that Senator Kennedy was a fighter and a great senator. "I do not m'assie'rais here as a presidential candidate without some battles that Ted Kennedy has fought," Senator Obama said on CNN television. "Is it not only a personal friend, but he is someone who has fought for the right to vote and civil rights when I was a child. I stand on his shoulders." ; Senator Kennedy, 76, was a figure of domination in the U.S. Senate over seven full limits. His endorsement of Senator Obama for the Democratic presidential nomination this year was a major moment in Senator Obama 's competition with Senator Hillary Clinton of New York. Senator Kennedy was the youngest brother of President John F. Kennedy, who was assassinated in 1963. A second brother, Bobby Kennedy, was assassinated in 1968 while running for the presidency. Senator Kennedy is dealt with in Boston 's General Hospital Massachusetts. Doctors have said in a report he was in good spirits and that his course of treatment had not been completed. "The preliminary results of a brain biopsy identified the cause of the seizure as malignant glioma in the left parietal lobe," they said.

Pain Relief/Muscle Relaxant

Zanaflex
Zanaflex (Tizanidine-Oral (tize-AN-ih-deen))
Zanaflex (Tizanidine-Oral) is a muscle relaxant is used to help relax certain muscles in your body.

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Drug Name

Zanaflex (Tizanidine-Oral (tize-AN-ih-deen))

Drug Uses

Zanaflex is a muscle relaxant is used to help relax certain muscles in your body. It relieves the spasms and increased muscle tone caused by medical problems such as multiple sclerosis or spinal injury. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How Taken

Zanaflex comes as a tablet to take it orally. It usually is taken two or three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Zanaflex exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Drug Class and Mechanism

Tizanidine is an agonist at (alpha) 2 -adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.

The imidazoline chemical structure of tizanidine is related to that of the anti-hypertensive drug clonidine and other (alpha) 2 -adrenergic agonists. Pharmacological studies in animals show similarities between the two compounds, but tizanidine was found to have one-tenth to one-fiftieth (1/50) of the potency of clonidine in lowering blood pressure.

Missed Dose

If you take several doses per day, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals. However, if you remember a missed dose when it is almost time for your next scheduled dose, skip the missed dose. Do not take a double dose to make up for a missed one.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Warnings/Precautions

Before taking this medication, tell your doctor if you have liver disease, have kidney disease, have low blood pressure or you are on medication to treat high blood pressure; or you are taking birth control pills. You may not be able to take Zanaflex, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. Zanaflex is in the FDA pregnancy C. This means that it is not known whether Zanaflex will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is not known whether Zanaflex passes into breast milk. Do not take Zanaflex without first talking to your doctor if you are breast-feeding a baby.

Possible Side Effects

Side effects from Zanaflex can occur. Tell your doctor if any of these symptoms are severe or do not go away: dizziness, upset stomach, vomiting, tingling sensation in the arms, legs, hands, and feet, dry mouth, increased muscle spasms. If you experience either of the following symptoms, call your doctor immediately: yellowing of the skin or eyes, unexplained flu-like symptoms.

More Information

If you experience any of the following serious side effects, stop taking tizanidine and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- hallucinations or abnormal behavior; or
- liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
Other, less serious side effects may be more likely to occur. Continue to take tizanidine and talk to your doctor if you experience
- drowsiness or dizziness;
- weakness;
- dry mouth;
- increased muscle tone or spasms; or
- sweating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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